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HCG
HCG

HCG

Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone composed of an alpha (α) and a beta (β) subunit. In humans, it is primarily produced by the syncytiotrophoblast cells of the placenta during pregnancy, playing a crucial role in maintaining the corpus luteum and supporting the early stages of gestation. Beyond its natural physiological role, HCG shares structural and functional similarities with pituitary gonadotropins, such as Luteinizing Hormone (LH) and, to a lesser extent, Follicle-Stimulating Hormone (FSH). This homology is key to its various applications in both clinical and research settings.

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Description

Quick Facts

HCG exerts its biological effects by binding to and activating the LH/Choriogonadotropin Receptor (LHCGR), which is found on the surface of various cells, particularly in the gonads (Leydig cells in the testes and theca/granulosa cells in the ovaries). Upon binding, it mimics the action of LH, stimulating steroidogenesis. In males, this leads to the production of testosterone by Leydig cells. In females, it can trigger ovulation and support the corpus luteum’s progesterone production, which is essential for maintaining early pregnancy. Its prolonged half-life compared to LH allows for a more sustained stimulatory effect.

 

  • Reproductive Endocrinology: Extensive research explores HCG’s role in male and female fertility, including studies on anovulation, male hypogonadism, cryptorchidism, and assisted reproductive technologies (ART).
  • Gonadal Function Studies: Used as a research tool to investigate testicular and ovarian function, Leydig cell steroidogenesis, and follicular development.
  • Andrology Research: Relevant for studies on testosterone production, spermatogenesis, and the hypothalamic-pituitary-gonadal (HPG) axis in males.
  • Endocrine Disruptor Research: Employed in studies examining the impact of various compounds on reproductive hormone pathways.
  • Veterinary Science: Applied in animal breeding and reproductive management for various species.
Why Choose Peptide Chains for HCG?

Peptide Chains provides high-purity HCG in bulk API quantities, essential for rigorous research, pharmaceutical development, and compounding applications. Our HCG is meticulously produced and supplied in a lyophilized format, ensuring exceptional stability, potency, and ease of reconstitution for your precise experimental protocols. We adhere to stringent quality control standards, guaranteeing the purity and consistency required for accurate and reproducible results in studies related to reproductive health, endocrinology, and hormone therapy.

Additional information

Weight 0.05 lbs
Dimensions 10 × 15 × 5 in
Size

100g, 500g, 1kg

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At Peptide Chains, we specialize in providing high-quality bulk Active Pharmaceutical Ingredients (APIs) and lyophilized compounds. We are dedicated to supplying the essential raw materials critical for innovation and development within the pharmaceutical, biotechnology, and compounding industries.

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Please note that all products offered on this website are intended solely for Research and Development purposes and must never be consumed by humans.

The U.S. Food and Drug Administration (FDA) has not evaluated the information on this site or the products we supply. Our products are not meant to diagnose, treat, cure, or prevent any medical condition.

Peptide Chains operates as a chemical supplier. We are not a compounding pharmacy or chemical compounding facility (under 503A) nor an outsourcing facility (under 503B) as defined by the Federal Food, Drug, and Cosmetic Act.