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IGF-LR3
IGF-LR3

IGF-LR3

IGF-LR3 (Insulin-like Growth Factor-1 Long R3) is a modified, longer-acting analogue of human Insulin-like Growth Factor-1 (IGF-1). Native IGF-1 is a crucial peptide hormone primarily produced in the liver, mediating many of the anabolic and growth-promoting effects of growth hormone (GH). IGF-LR3 differs from natural IGF-1 by containing an arginine (Arg) instead of a glutamic acid (Glu) at position 3, and a 13-amino acid extension at its N-terminus.

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Description

Quick Facts

IGF-LR3 primarily exerts its effects by binding to the IGF-1 receptor (IGF-1R), a tyrosine kinase receptor found on the surface of most cells in the body. Upon binding, it initiates intracellular signaling cascades, most notably the PI3K/Akt and MAPK pathways, which are central to regulating cell growth, differentiation, proliferation, and survival. By minimizing binding to IGFBPs, IGF-LR3 ensures a greater proportion of the peptide remains free and active, leading to more potent and sustained anabolic signaling. Its actions are particularly pronounced in tissues like skeletal muscle, cartilage, and bone, promoting protein synthesis and tissue repair.

 

  • Muscle Growth & Regeneration: Extensively studied for its potent anabolic effects, including promoting muscle hypertrophy, enhancing protein synthesis, and supporting muscle repair after injury.
  • Tissue Healing & Repair: Research explores its role in accelerating the healing of various tissues, including tendons, ligaments, and cartilage, by stimulating cellular proliferation and extracellular matrix production.
  • Metabolic Regulation: Investigated for its influence on glucose metabolism, insulin sensitivity, and fat breakdown, making it relevant for studies on metabolic disorders.
  • Cellular Longevity & Anti-Aging: Explored in the context of cellular maintenance, repair mechanisms, and broader applications in healthy aging research due to its growth-promoting and protective properties.
  • Neurological Studies: Emerging research investigates its potential neuroprotective effects and role in neuronal plasticity.

 

Why Choose Peptide Chains for IGF-LR3?

Peptide Chains provides high-purity IGF-LR3 in bulk API quantities, essential for comprehensive research and development. Our IGF-LR3 is supplied in a stable, lyophilized format, ensuring optimal integrity and ease of handling for precise experimental protocols. We maintain rigorous quality control standards, including detailed analytical testing, to guarantee the exceptional purity, potency, and batch-to-batch consistency that is critical for reliable and reproducible outcomes in advanced studies concerning muscle anabolism, tissue regeneration, and metabolic health.

Additional information

Weight 0.05 lbs
Dimensions 10 × 15 × 5 in
Size

100g, 500g, 1kg

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At Peptide Chains, we specialize in providing high-quality bulk Active Pharmaceutical Ingredients (APIs) and lyophilized compounds. We are dedicated to supplying the essential raw materials critical for innovation and development within the pharmaceutical, biotechnology, and compounding industries.

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Please note that all products offered on this website are intended solely for Research and Development purposes and must never be consumed by humans.

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