Pinealon

Pinealon is a synthetic tripeptide (Glu-Asp-Arg) that belongs to the class of bioregulatory peptides. It is an orally active peptide developed by Russian scientists, stemming from extensive research into short peptides derived from specific animal tissues, in this case, the pineal gland. The pineal gland is a small endocrine gland in the brain that plays a crucial role in regulating sleep patterns (melatonin production), circadian rhythms, and influencing various endocrine functions and overall brain health. Pinealon is designed to mimic certain beneficial aspects of pineal gland activity, particularly in modulating brain function and neuroprotection.

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SKU: 174-1 Category:Bulk API

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Quick Facts

Pinealon’s mechanism of action is believed to be multifaceted, primarily focusing on its ability to interact with and influence neuroendocrine and neurological pathways. While the exact molecular targets are still being elucidated, research suggests that Pinealon:

Modulates Pineal Gland Function: It is thought to exert a regulatory effect on the pineal gland itself, potentially optimizing its endogenous peptide and hormone production (e.g., melatonin).
Neuroprotective Effects: Pinealon has demonstrated neuroprotective properties, helping to shield neurons from various damaging factors, including oxidative stress, excitotoxicity, and ischemia. This protection may involve stabilizing neuronal membranes and supporting mitochondrial function.
Gene Expression Regulation: As a bioregulatory peptide, Pinealon is hypothesized to influence gene expression, specifically those genes involved in nervous system function, cellular repair, and antioxidant defense. This allows for a more systemic and adaptive response to stress or damage.
Cognitive Enhancement: By supporting neuronal health and function, it is thought to contribute to improved cognitive processes such such as memory, attention, and overall mental performance.
Antioxidant Activity: It may directly or indirectly enhance the body’s antioxidant defense systems, crucial for reducing neuronal damage caused by free radicals.

Neurodegenerative Diseases: Investigated for its potential therapeutic role in conditions such as Alzheimer’s disease, Parkinson’s disease, and other forms of cognitive impairment by protecting neurons and supporting brain function.
Cognitive Decline: Research explores its use in mitigating age-related cognitive decline, improving mental clarity, and enhancing memory.
Stroke & Brain Injury: Studies focus on its neuroprotective effects in preventing neuronal damage and promoting recovery following ischemic events or traumatic brain injuries.
Stress and Mood Disorders: Due to its influence on neuroendocrine systems, it is explored for its potential to alleviate symptoms of chronic fatigue, anxiety, and depression by normalizing brain function.
Sleep and Circadian Rhythm Regulation: Given its pineal gland origin, some research touches upon its indirect influence on sleep patterns and circadian rhythm optimization.

Why Choose Peptide Chains for Pinealon?

Peptide Chains provides high-purity Pinealon in bulk API quantities, essential for rigorous neuroscientific and pharmaceutical research. Our Pinealon is meticulously synthesized and supplied in a stable, lyophilized format, ensuring optimal integrity, purity (typically ≥98%), and ease of reconstitution for your precise experimental protocols. We are committed to stringent quality control, including comprehensive analytical testing, to guarantee the exceptional purity, potency, and batch-to-batch consistency that is critical for reliable and reproducible results in studies focused on neuroprotection, cognitive enhancement, healthy brain aging, and the complex regulation of neuroendocrine systems.