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HomeBulk APISemax
Semax

Semax

Semax is a synthetic heptapeptide with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. It is an analogue of the adrenocorticotropic hormone (ACTH) fragment (4-10) and is notably different from the full ACTH molecule in that it retains the beneficial central nervous system effects without exhibiting hormonal activity related to cortisol production. Developed in Russia, Semax has been the subject of extensive research for its pronounced neuroprotective and nootropic (cognitive enhancing) properties, making it a compound of significant interest in neurological and psychiatric research.

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SKU: 137 Category:Bulk API
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Description

Quick Facts

Semax’s multifaceted mechanism of action primarily targets various neurochemical and molecular pathways within the brain. Key actions include:

  • Neurotrophic Factor Modulation: It rapidly elevates the levels of brain-derived neurotrophic factor (BDNF) and its receptor TrkB in the hippocampus and cortex. BDNF is crucial for neuronal growth, survival, differentiation, and synaptic plasticity, playing a vital role in learning, memory, and overall brain health.
  • Neurotransmitter System Modulation: Semax is observed to influence the activity of monoaminergic systems, including dopaminergic and serotonergic pathways. It can enhance the release and turnover of these neurotransmitters, contributing to improved mood, reduced anxiety, and enhanced cognitive functions.
  • Neuroprotection and Antioxidant Effects: Semax exhibits robust neuroprotective properties, safeguarding neurons from oxidative stress, inflammation, and damage caused by various insults (e.g., ischemia, heavy metal toxicity). It helps restore damaged neurological functions by potentially acting as an antioxidant and by influencing gene expression related to cellular repair and stress response.
  • Angiogenesis and Circulation: Research indicates it may improve cerebral circulation and promote angiogenesis, enhancing oxygen and nutrient delivery to brain tissues.
  • Anti-Amyloid Aggregation: Emerging research suggests Semax’s ability to complex with copper ions and interfere with the aggregation and fibrillogenesis of amyloid-beta protein, which is implicated in neurodegenerative conditions like Alzheimer’s disease.
  • Cognitive Enhancement: Extensive studies on its ability to improve memory, attention, learning, and overall mental performance, making it a focus for cognitive disorders and healthy cognitive optimization.
  • Neuroprotection & Stroke Recovery: Research into its efficacy in protecting brain cells from damage during acute cerebral hypoxia (e.g., ischemic stroke) and promoting recovery of neurological functions post-injury.
  • Anxiety & Depression: Investigated for its anxiolytic and antidepressant effects, potentially by modulating neurotransmitter balance and stress responses.
  • Neurodegenerative Diseases: Explored for its potential therapeutic role in conditions such as Alzheimer’s and Parkinson’s disease due to its neuroprotective, anti-inflammatory, and anti-aggregation properties.
  • Stress Management: Research on its ability to mitigate the negative physical and mental responses to chronic stress.
Why Choose Peptide Chains for Semax?

Peptide Chains provides high-purity Semax in bulk API quantities, essential for rigorous and advanced neurological and cognitive research. Our Semax is meticulously synthesized and supplied in a stable, lyophilized format, ensuring optimal integrity, purity (typically ≥97%), and ease of reconstitution for your precise experimental protocols. We are committed to stringent quality control, including comprehensive analytical testing, to guarantee the exceptional quality and batch-to-batch consistency that is critical for reliable and reproducible results in studies focused on neuroprotection, cognitive enhancement, and the complex mechanisms of brain health.

Additional information

Weight 0.05 lbs
Dimensions 10 × 15 × 5 in
Size

100g, 500g, 1kg

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